National Joint Registry (NJR) Data Shows Positive Outcomes in Revision

A look at data found around implant material and infection.

By Christine Boehm, Brand Manager, Porous Metal Technologies - Advanced Process Technologies, Zimmer Biomet

Trabecular Metal™ Material is a unique, highly porous biomaterial made from elemental tantalum with structural, functional and physiological properties similar to bone. The material features a 100 percent open, engineered and interconnected pore structure to support bony in growth and vascularization4 and has been used in a variety of orthopedic applications for 20 years.

National Joint Registry (NJR) data has shown positive outcomes associated with the use of its Trabecular Metal Cups in more than 9,500 patients undergoing revision hip arthroplasty from 2003 to 2015. The data stemmed from a report by the NJR for England, Wales, Northern Ireland and the Isle of Man and documented that Trabecular Metal Cups were associated with significantly lower infection rates and overall re-revision rates.

Specifically, the independent analysis conducted by NJR demonstrated the following*:

  • Trabecular Metal Cups used in revision total hip arthroplasty (THA) have been shown to be 21 percent less likely to be re-revised due to infection (statistically significant, p-value=0.036).1,2
  • For high risk patients with a first revision indication of infection, Trabecular Metal Cups appear to be 35 percent less likely to be re-revised for infection. Due to the limited sample size, this finding has not reached statistical significance (not statistically significant, p-value=0.108).3
  • Trabecular Metal Cups used in revision THA have been shown to be 11 percent less likely to be re-revised for any reason (statistically significant, p-value=0.015).1
*The NJR report retrospectively analyzed outcomes related to 9,573 revision procedures using cementless Trabecular Metal Cups and 30,452 revision procedures using non-Trabecular Metal cementless cups, from April 2003 through July 2015. The complete NJR report can be found at www.zimmerbiomet.com/TM.
 
  1. According to NJR data from 2003 to 2015 where 9,573 Trabecular Metal and 30,452 non-Trabecular Metal cups were used in revision THA and based on hazard ratios adjusted by patient gender, age group, and indications (osteoarthritis/non-osteoarthritis).
  2. NJR data shows a higher percentage of Trabecular Metal cups were used with antibiotic bone cement compared to all other non-Trabecular Metal cement less cups.
  3. According to NJR data from 2003 to 2015 where 628 Trabecular Metal and 2,114 non-Trabecular Metal cups were used in revision THA and based on hazard ratios adjusted by patient gender, age group, and indications (osteoarthritis/non-osteoarthritis).
  4. Karageorgiou, V. and Kaplan, D. “Porosity of 3D Biomaterial Scaffolds and Osteogenesis.” Biomaterials, 26 (27): 5474-91, September 2005

 

Legal Manufacturer

Zimmer, Inc.
1800 W. Center Street
Warsaw, IN 46580
USA

 

Legal Manufacturer

Zimmer Trabecular Metal Technology, Inc.
10 Pomeroy Road
Parsippany, New Jersey 07054
USA

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